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Proprietary Blend Supplements: What a Blend Total Hides

Quick answer

Proprietary blend supplements list one total weight for a group of ingredients and keep each amount private. US rules allow this if the ingredients appear in order of weight. Glyco Defender's blend weighs 15.47 mg for 21 lines, so the first line holds at most 15.47 mg and the last far less.

Written by the Glyco Defender label deskUpdated · 4 min read

Supplement Facts panel from the Glyco Defender bottle
The Supplement Facts panel from the bottle label. The blend total is printed once for all 21 lines.

What is a proprietary blend in a supplement?

A proprietary blend is a group of ingredients listed under one combined weight, with no amount shown for each one.

Federal labeling rules let a maker do this, as long as the ingredients appear in descending order of weight (21 CFR 101.36 (eCFR)). The rule asks for the total and the order. It does not ask for the split.

How much of each ingredient is in a proprietary blend?

You cannot know the exact amount, but you can find a ceiling. A line in place k of the list holds at most the blend total divided by k.

The reason is simple. Everything above it weighs at least as much, so k lines of that size would already pass the total. Glyco Defender's blend is 15.47 mg.

Most each Glyco Defender line can hold per 1 mL serving.
PlaceLineAt most
1Maca root extract15.5 mg
2African mango seed extract7.7 mg
7Green tea leaf extract2.2 mg
8Gymnema sylvestre leaf extract1.9 mg
12Ginseng root extract1.3 mg

Are proprietary blend supplements a problem?

A blend is not illegal or unsafe by itself, but it does limit what a shopper can check.

Studies of gymnema used 200 to 400 mg of extract (Drugs.com, Gymnema monograph). The most this label allows for gymnema is 1.9 mg, so the studies cannot be applied to this bottle. The same gap holds for the other lines.

Supplements are sold without prior FDA approval (FDA, Using Dietary Supplements).

Keep taking prescribed medicine

Never stop or change a medicine because of a supplement. Tell your doctor about every product you use.

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How do you judge a proprietary blend before you buy?

Do the ceiling math, compare it with a study dose, and prefer labels that print each amount.

  • Divide the blend total by each line's place.
  • Check whether the ceiling is close to a studied dose.
  • Read the full list on the supplement facts page.
  • Ask what the maker will publish: amounts, lab reports, the manufacturer's name.

The ingredients page runs this math for all 22 lines.

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FAQ01

Questions about proprietary blends

Why do supplement makers hide the dose of each ingredient?

Makers usually say it protects a formula from copying. Labeling rules only require the blend total and the order by weight (21 CFR 101.36 (eCFR)). The result is that shoppers cannot match a dose to research.

Does a longer ingredient list in a blend mean more of each?

No. A longer list divides the same total more ways. With 21 lines sharing 15.47 mg, an even split is about 0.74 mg each. Adding names does not add milligrams.

Can I ask a seller for the exact blend amounts?

You can, and it is a fair question. The label does not print them, and no lab report is published for this product. Ask the distributor listed on the bottle, and judge the answer with the ceiling math.

Who wrote this02

Written and reviewed by

Written byThe Glyco Defender label deskIglycodefender, licensed U.S. retail desk for Glyco Defender

Pages built from the label, the sales page and linked NIH, FDA, CDC, FTC and peer-reviewed sources.

Medically reviewed byDr. Andres Palacio, MD, PhysicianRole: Medical reviewerReview date: October 19, 2026

Last updated . Read our editorial standards and how we check reviews. This website is run by a licensed U.S. retail desk for Glyco Defender, not by the manufacturer or the label's distributor. Buying through our order links earns us money.

Licensed U.S. retail desk for Glyco Defender

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