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Glyco Defender Proprietary Blend: What 15.47 mg Can Hold
The Glyco Defender proprietary blend is a 15.47 mg mix of 21 ingredients in each 1 mL serving. US rules let a label show only the total weight and the order, so single amounts stay hidden. Split evenly, each line gets about 0.74 mg, far below the hundreds of milligrams studied for key herbs.
Written by the Glyco Defender label deskUpdated · 4 min read
What is a proprietary blend on a supplement label?
A proprietary blend is a group of ingredients listed under one name with one total weight. The rule lets the maker hide each ingredient's own amount, as long as the list runs in descending order by weight (21 CFR 101.36 (eCFR)).
Glyco Defender's blend totals 15.47 mg per mL and names 21 lines. It is legal. It also means you cannot check any one dose against a study.
How much of each ingredient is in the blend?
No line can hold more than 15.47 mg divided by its place in the list. That is a ceiling, not a measurement.
An even split gives about 0.74 mg each. The real split is uneven, so early lines hold more and late lines less. Maca, first, tops out at 15.5 mg. Green tea, seventh, tops out at 2.2 mg.
Do blend amounts match the doses in studies?
No. Every studied dose we can verify is far larger than the most the blend can hold.
| Ingredient | At most here | Studied |
|---|---|---|
| Gymnema (8th) | 1.9 mg | 200-400 mg extract (Drugs.com, Gymnema monograph) |
| African mango (2nd) | 7.7 mg | 300 mg a day (NIH ODS, Dietary Supplements for Weight Loss) |
| Ginseng (12th) | 1.3 mg | from about 100 mg (Shishtar et al., PLoS One 2014) |
Extract ratios do not close the gap. A 20:1 concentrate describes plant input, not strength, and the label weight stays the same (Monagas et al., Front Pharmacol 2022).

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See packsWhat should you ask a brand that uses a proprietary blend?
Ask for the per-ingredient amounts and for a lab report. A brand that wants you to judge the dose can share both.
The blend is a legal format, not a hidden strength. With no trial of the product, it should be judged as 15.47 mg in total, not as 21 full doses.
The comparison guide shows how to read any label this way. See also the ingredients page.
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FAQ01
More on the blend
Is a proprietary blend illegal or a sign of a bad product?
No. It is allowed under the FDA labeling rule, which asks only for the total weight and descending order (21 CFR 101.36 (eCFR)). It is not proof of a bad product. It is a reason to be cautious about dose claims.
Can I work out the exact amount of one ingredient?
No. You can only set a ceiling. The ingredient in place k holds at most 15.47 mg divided by k. The label prints no exact figure for any line, so any number you see elsewhere is a guess.
Does the chromium count as part of the blend?
No. Chromium is listed apart from the blend, at 7 mcg and 20% of the Daily Value. It is the only line with a printed amount, and trials of chromium used 200 to 1,000 mcg a day (NIH ODS, Chromium).
Who wrote this02
Written and reviewed by
Pages built from the label, the sales page and linked NIH, FDA, CDC, FTC and peer-reviewed sources.
Last updated . Read our editorial standards and how we check reviews. This website is run by a licensed U.S. retail desk for Glyco Defender, not by the manufacturer or the label's distributor. Buying through our order links earns us money.
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